| Clinicopathlogic characteristics of multiple synchronous early gastric cancers |
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Hoi Jin Kim, Jun Haeng Lee, June Sang Lee, Tae Gun Moon, Jae J Kim, Jong Chul Rhee, Jae Hyung Noh, Tae Sung Sohn, Sung Kim |
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고려대학교 의과대학 내과학교실 |
| 원저 : 다발성 동시성 조기위암에 대한 임상적 고찰 |
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김회진, Jun Haeng Lee, June Sang Lee, Tae Gun Moon, Jae J Kim, Jong Chul Rhee, Jae Hyung Noh, Tae Sung Sohn, Sung Kim |
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| Abstract |
Background : With the progress of limited surgery and endoscopic treatment for early gastric cancer (EGC), multiple synchronous EGCs, a cause of recurrence, become more important. The objective of this study was to elucidate the characteristics of multiple synchronous EGCs with an emphasis on features of preoperatively undiagnosed lesions.
Methods
: We retrospectively reviewed medical records of 496 patients who underwent a gastrectomy for EGC at our institution between January 2004 and December 2004.
Results
: Twenty-four patients (4.8%) had multiple synchronous EGCs with 24 main and 27 accessory lesions. Multiple synchronous EGCs showed male predominance (p=0.03). Other characteristics including lymph node metastasis were the same as with single EGC. Out of 27 accessory lesions, six lesions (22%) were not detected preoperatively in six patients (25%). Macroscopically five lesions were flat and one lesion was depressed.
Five lesions were located at the anterior or posterior wall of the middle and low third portion and one lesion was located at the lesser curvature side of the upper third portion of the stomach. Two lesions were 4 mm, one lesion was 8 mm, two lesions were 12 mm and one lesion was 15 mm in size (mean diameter = 9.1 mm). Histologically, four lesions were of the differentiated type and two lesions were of the undifferentiated type.
Conclusions
: Multiple synchronous EGCs have same clinicopathologic features as a single EGC except for male predominance. Considering the possibility of a synchronous lesion, one should examine the entire stomach precisely with special attention to the anterior, posterior wall and lesser curvature side of the same or neighboring area of a known EGC lesion before treatment.(Korean J Med 72:360-367, 2007)
Key Words : Early gastric cancer, Multiple early gastric cancers, Synchronous gastric cancer
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| Key Words:
Early gastric cancer, Multiple early gastric cancers, Synchronous gastric cancer |
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