| The prevalence of microalbuminuria and associated factors in newly diagnosed type 2 diabetes mellitus in Korea |
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Dong Jin Kim, Seong Jin Ryu, Young Jin Seo, Nam Hoon Kim, Hye Soo Chung, Chai Ryoung Eun, Hye Jung Choi, Hye Sook Kim, Sae Jeong Yang, Juri Park, Hye Jin Yoo, Soo Yeon Park, Yun Jeon |
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Department of internal medicine1, department of pathology2, Yonsei University College of Medicine |
| 원저 : 새로 진단받은 제2형 당뇨병에서 미세알부민뇨와 관련 인자 |
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김동진&#;유성진&#;서영진&#;김남훈&#;정혜수&#;은채령&#;최혜정&#;김혜숙 양세정&, Seong Jin Ryu, Young Jin Seo, Nam Hoon Kim, Hye Soo Chung, Chai Ryoung Eun, Hye Jung Choi, Hye Sook Kim, Sae Jeong Yang, Juri Park, Hye Jin Yoo, Soo Yeon Park, Yun Jeon |
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| Abstract |
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Background : To determine the prevalence and the associated factors of microalbuminuria in Korean subjects with
newly diagnosed type 2 diabetes mellitus.
Methods : A total of 304 patients with newly diagnosed type 2 diabetes mellitus that visited Anam Hospital, Korea
University Medical Center, were studied cross-sectionally for the presence of microalbuminuria and other micro- and
macrovascular complications. Microalbuminuria was calculated by the amount of albumin excretion in the urine for 24 hrs
(30-299 mg/24hr) or by the albumin creatinine ratio in a spot urine sample (30-299 mg/g creatinine). Subjects were
divided into two groups: the normoalbuminuria group and the microalbuminuria group.
Results : The prevalence of microalbuminuria, normoalbuminuria and overt proteinuria in patients with newly
diagnosed type 2 diabetes mellitus was 17.1%, 80.3% and 2.6%. respectively. Microalbuminuria was significantly
correlated with the body mass index (BMI), fasting insulin level, fasting C-peptide level and triglyceride level. The
number of metabolic syndrome components was significantly correlated with the amount of microalbuminuria. In patients
with microalbuminuria and without retinopathy, the correlation of microalbuminuria and the presence of metabolic
syndrome was also significant.
Conclusions : The prevalence of microalbuminuria in 304 Korean patients with newly diagnosed type 2 diabetes
mellitus was 17.1%, and microalbuminuria had a correlation with the BMI, fasting insulin level, fasting C-peptide level,
HOMA level, triglyceride level and the presence of metabolic syndrome.(Korean J Med 73:503-511, 2007) |
| Key Words:
Microalbuminuria, Prevalence, Diabetes mellitus, type 2, Metabolic syndrome |
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