| The clinical effects of body mass index in patients with acute myocardial infarction after percutaneous coronary intervention |
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Seon Young Jeong, R.N., Jung Ae Rhee, Myung Ho Jeong, Seon Ho Hwang, Nam Sik Yoon, Seo Na Hong, Sang Rok Lee, Kye Hun Kim, Jae Youn Moon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Young |
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Department of internal medicine1, department of pathology2, Yonsei University College of Medicine |
| 원저 : 관상동맥 중재술을 받은 급성 심근경색증 환자에서 체질량 지수의 영향 |
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정선영&#;이정애&#;정명호&#;황선호&#;윤남식&#;홍서나&#;이상록&#;김계훈 문재연&, R.N., Jung Ae Rhee, Myung Ho Jeong, Seon Ho Hwang, Nam Sik Yoon, Seo Na Hong, Sang Rok Lee, Kye Hun Kim, Jae Youn Moon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Young |
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| Abstract |
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Background : Obesity is one of the major risk factors for coronary artery disease. However, the long-term clinical effects of obesity after percutaneus coronary intervention (PCI) in Korean patients with acute myocardial infarction (AMI) have not been sufficiently evaluated.
Methods : A total of 309 patients (mean age 60.5±11.3 years, M:F=243:66) that underwent PCI with a diagnosis of AMI between February 2002 and June 2006. Thepatients were divided into two groups according to the body mass index (BMI): group I (n=194; BMI <25 kg/m2; mean age 61.7±11.1 years, M:F=151:43) and group II (n=115; BMI≥25 kg/m2, mean age 58.2±11.3 years, M:F=92:23). Clinical characteristics and risk factors, and major adverse cardiac events during a six-month follow-up were compared between patients in the two gropus.
Results : The mean age of group I patients was older than that of group II patients (61.7±11.1 years vs. 58.6±11.5 years, p=0.017). The prevalence of hypertension was higher in group II patients (75/194, 38.7% vs.59/115, 51.3%, p=0.033) and hyperlipidemia was more prevalent in group II patients (75/194, 38.7% vs. 60/115, 52.2%, p=0.024). The levels of total cholesterol (184.3±39.9 mg/dL vs. 201.4±42.6 mg/dL, p=0.001), triglycerides (121.2±61.6 mg/dL vs. 147.1±96.2 mg/dL, p=0.005), low-density lipoprotein-cholesterol (120.3±35.1 mg/dL vs. 134.1±37.8 mg/dL, p=0.002) were lower in group I patients than in group II patients. The restenosis rate on a follow-up coronary angiogram was higher in group II patients (18/69, 26.1%) than in group I patients (14/109, 12.8%, p=0.025).
Conclusions : Obesity is associated with hyperlipidemia and hypertension in patients with AMI. The restenosis rate after PCI was higher in obese AMI patients. (Korean J Med 73:603-610, 2007)
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| Key Words:
Myocardial infarction, Obesity, Prognosis |
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