| A case of infective endocarditis caused by Aspergillus fumigatus in a liver transplant recipient |
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Kyung-Wook Hong, Jeong-A Lee, Hye-Won Park, Hye-Lee Kwon, Seong-Jin Cho, Jae-Seok Kim, Joong-Sik Eom |
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경희대학교 의과대학 순환기내과학교실 |
| 증례 :간 이식 환자에서 발생한 아스페르길루스 심내막염 1예 |
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홍경욱.이정아.박혜원.권혜리.조성진.김재석.엄중식, Jeong-A Lee, Hye-Won Park, Hye-Lee Kwon, Seong-Jin Cho, Jae-Seok Kim, Joong-Sik Eom |
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| Abstract |
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It is known that the incidence of fungal endocarditis is increasing as the precipitating factors, such as organ transplantation, use of immunosuppressive agents, previous cardiac surgery, AIDS, chemotherapy, and long-term antibiotic use are on the rise. However, the diagnosis and adequate treatment of fungal endocarditis is likely to be delayed as blood cultures are rarely positive.
We report a case of native valve endocarditis in a patient who underwent liver transplantation and was taking immunosuppressive agents. Because of no improvement despite empirical antibiotic treatment, a mitral valve replacement was performed. Tissue culture and biopsy of the vegetations revealed Aspergillus spp., and A. fumigatus was identified by analysis of internal transcribed spacer DNA sequences of the pathogenic fungus using a polymerase chain reaction. Despite surgical intervention, she died of an acute cerebral infarction with cerebral edema. (Korean J Med 75:115-118, 2008)
Key Words : Aspergillus fumigatus; Endocarditis; Liver transplantation |
| Key Words:
Aspergillus fumigatus; Endocarditis; Liver transplantation |
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