Korean J Med > Volume 75(6); 2008 > Article
The Korean Journal of Medicine 2008;75(6):700-703.
Wernicke’s encephalopathy in a patient with acute alcoholic pancreatitis
Jihyun Ahn, Jeong Wook Kim
한림대학교 의과대학 내과학교실 강동성심병원 심혈관센터
급성 알코올성 췌장염 환자에서 발병한 베르니케 뇌병증 1예
안지현, 김정욱
Abstract
Wernicke’s encephalopathy is a serious neurological disorder caused by thiamine deficiency that is characterized by the triad of ocular abnormalities, ataxia, and global confusional state. It is most often seen in alcoholics, but it can be seen in disorders associated with malnutrition and with prolonged intravenous feeding without appropriate vitamin supplementation. We report the case of a 51-year-old man with acute alcoholic pancreatitis and chronic alcoholism with an intraperitoneal abscess, who presented with Wernicke’s encephalopathy. He was initially treated by fasting, intravenous fluid replacement, and intermittent vitamin infusion for 3 weeks. After subsequently starting a high carbohydrate oral diet, the patient developed diplopia, orientation disturbance, ataxia, a confusional state, and nystagmus. His neurologic signs and symptoms normalized gradually after intravenous thiamine supplementation. (Korean J Med 75:700-703, 2008)
Key Words: Wernicke’s encephalopathy; Thiamine; Alcoholic pancreatitis


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