| A case of hepatocellular carcinoma confirmed histologically in primary biliary cirrhosis |
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You Jung Ha, Jun Yong Park, Semi Park, Kyung Min Kim, Ju Yeon Pyo, Young Nyun Park, Kwang Hyub Han |
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| 증례 : 원발담즙간경변증에서 조직학적으로 확진된 간세포암종 1예 |
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하유정.박준용.박세미.김경민.표주연.박영년.한광협, Jun Yong Park, Semi Park, Kyung Min Kim, Ju Yeon Pyo, Young Nyun Park, Kwang Hyub Han |
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| Abstract |
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Primary biliary cirrhosis is a chronic cholestatic autoimmune liver disease characterized by progressive bile duct injury caused by portal and periportal inflammation, resulting in fibrosis and eventual cirrhosis in a significant proportion of patients. Little is known of the incidence, survival, and risk factors of hepatocellular carcinoma in patients with primary biliary cirrhosis. We report the case of a 68-year-old male with primary biliary cirrhosis who developed hepatocellular carcinoma without hepatitis B or C virus infection. Histological analysis revealed well-differentiated hepatocellular carcinoma. He was treated successfully with percutaneous radiofrequency ablation and has regular follow-up evaluations without recurrence. This is the first case report of hepatocellular carcinoma in primary biliary cirrhosis diagnosed with a liver biopsy in Korea. (Korean J Med 75:S733-S737, 2008) |
| Key Words:
Primary biliary cirrhosis; Hepatocellular carcinoma; Liver biopsy |
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