Allopurinol-induced agranulocytosis in a patient on peritoneal dialysis |
Jin Kyung Kim, Young Ki Lee, Jung Woo Noh, Byung Moo Ahn, Jung Han Kim, Young Ok Jung, Min-Jeong Park |
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복막투석 환자에서 allopurinol 복용 후 발생한 무과립구증 1예 |
김진경, 이영기, 노정우, 안병무, 김정한, 정영옥, 박민정 |
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Abstract |
Agranulocytosis is a rare, but sometimes dangerous, adverse reaction to allopurinol. We report the unusual case of a 43-year-old man with agranulocytosis, who received allopurinol while undergoing peritoneal dialysis. The bone marrow biopsy indicated that the agranulocytosis was drug-induced. After ceasing all drugs, isolating the patient, and administering granulocyte colony-stimulating factor (G-CSF), the leukocyte count returned to normal. A relationship between allopurinol therapy and agranulocytosis was presumed.
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Key Words:
Allopurinol; G-CSF (granulocyte colony-stimulating factor); Agranulocytosis |
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