Streptococcus salivarius pneumonia with pulmonary nocardiosis in a rheumatoid arthritis patient treated with immunosuppressants |
Ina Jeong, Eun Young Heo, Jae Seok Lee, Hye-Ryoun Kim, Eun Young Lee, Young Whan Kim, Seok-Chul Yang |
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면역억제제 치료 중인 류마티스 관절염 환자에서 발생한 Streptococcus salivarius 및 Nocardia 폐렴 1예 |
정인아, 허은영, 이재석, 김혜련, 이은영, 김영환, 양석철 |
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Abstract |
Streptococcus salivarius is a Gram-positive organism that belongs to the viridians group of streptococci. It is a relatively non-virulent bacterium that is part of the normal flora. It is rarely isolated from blood and is usually considered a contaminant. Nevertheless, S. salivarius may cause life-threatening infections, especially in immunocompromised hosts. There have been relatively few reports of S. salivarius pneumonia. Nocardiosis is also a rare opportunistic infection. Pulmonary nocardiosis is difficult to diagnose and, consequently, the diagnosis is often delayed. We report an unusual presentation with multiple pulmonary mass-like consolidations caused by a mixed infection of S. salivarius and Nocardia sp. in a 58-year-old man with rheumatoid arthritis who was taking oral corticosteroid, methotrexate, and leflunomide. The patient’s symptoms and radiographic findings improved after six weeks of antibiotic therapy. (Korean J Med 77:128-132, 2009) |
Key Words:
Streptococcus salivarius; Nocardia; Rheumatoid arthritis |
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