| A case of intramedullary nocardiosis in a patient after hematopoietic stem cell transplantation |
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Yi Rang Kim, Young-Joo Jin, Donghoi Kim, Sang-Su Jung, Yong-Giun Kim, Kyoungwon Jung, Kyoo-Hyung Lee |
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| 조혈모세포이식 후 발생한 척수 내 Nocardia 감염증 1예 |
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김이랑, 진영주, 김동회, 정상수, 김용균, 정경원, 이규형 |
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| Abstract |
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Nocardiosis is uncommon in healthy people but occurs as an opportunistic infection in patients after hematopoietic stem cell transplantation, solid organ transplantation, malignancy, or acquired immune deficiency syndrome. Involvement of Nocardia in the spinal cord is rare; to our knowledge, only six cases have been reported. We report here the case of a 54-year-old man with a spinal cord abscess and epidural and paraspinal abscesses in the thoracic and lumbar spinal cord, causing paraplegia, voiding and defecation difficulties, and combined lung involvement, which developed 5 months after allogeneic hematopoietic stem cell transplantation. Nocardia grew in a fungus culture obtained by percutaneous lung biospy and CT-guided aspiration of the spinal abscess. A double combination regimen of antibiotic therapy (imipenem/cilastatin sodium, amikacin) was given. His paraplegia and his voiding and defecation difficulties improved considerably. To our knowledge, this is the first reported case of spinal cord Nocardiosis observed after allogeneic hematopoietic stem cell transplantation. |
| Key Words:
Nocardiosis is uncommon in healthy people but occurs as an opportunistic infection in patients after hematopoietic stem cell transplantation, solid organ transplantation, malignancy, or acquired immune deficiency syndrome. Involvement of Nocardia in the s |
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