A Case of Autoimmune Hepatitis Combined with Ulcerative Colitis

Korean J Med > Volume 80(2); 2011 > Article

Original Article

The Korean Journal of Medicine 2011;80(2):106-110.

A Case of Autoimmune Hepatitis Combined with Ulcerative Colitis

Ki Jun Lee1, June Sung Lee1, Won Ki Bae1, Nam Hoon Kim1, Kyung A Kim1, Young Soo Moon1, Mee Joo2

궤양성 대장염과 동반된 자가면역 간염 1예

이기준1, 이준성1, 배원기1, 김남훈1, 김경아1, 문영수1, 주미2

Abstract

Autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and primary biliary cirrhosis (PBC) are the major immune-mediated chronic liver diseases. They are characterized by circulating autoantibodies, hypergammaglobulinemia, unique clinical features, and associations with other autoimmune diseases, such as inflammatory bowel disease and autoimmune thyroiditis. Primary biliary cirrhosis is known to be associated with inflammatory bowel disease, such as ulcerative colitis. On the other hand, autoimmune hepatitis is rarely associated with ulcerative colitis. Here, we report a case diagnosed as autoimmune hepatitis combined with ulcerative colitis on the basis of histological and endoscopic findings.

Key Words: Autoimmune hepatitis; Ulcerative colitis