Korean J Med > Volume 80(2); 2011 > Article
The Korean Journal of Medicine 2011;80(2):188-193.
A Case of the Sweet’s Syndrome Associated with Anti tuberculous Medication
Mi Kyoung Kim1, Gi Hyun Kim1, Eun Joo Jang2, Ji Yeoun Lee2, Kang Hyeon Choe1,3, Ki Man Lee1,3, Jin Young An1,3
항결핵 치료 중 발생한 스위트 증후군 1예
김미경1, 김기현1, 장은주2, 이지연2, 최강현1,3, 이기만1,3, 안진영1,3
Abstract
Clinical manifestations of Sweet’s syndrome typically include fever, leukocytosis, and tender, erythematous plaques with a dermal infiltration of mature neutrophils. Sweet’s syndrome is divided into three clinical categories: idiopathic, malignancyassociated, and drug-induced. No correlation between antituberculous medication and Sweet’s syndrome has previously been reported. Here, we describe a 79-year-old woman who developed an acute onset of fever and skin eruption after taking antituberculous medication. The clinical pattern and the result of skin biopsy were consistent with Sweet’s syndrome. After cessation of rifampin, the fever and skin rash disappeared. Thus, we diagnosed the patient with Sweet’s syndrome, caused by rifampin. To our knowledge, this is the first reported case of rifampin-induced Sweet’s syndrome.
Key Words: Rifampin; Sweet’s syndrome


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