| Rituximab Plus CHOP for the Treatment of Primary Mediastinal Large B Cell Lymphoma in a Pregnant Woman |
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Eun Kyoung Kim1, Seok Jin Kim1, Sung Bum Park1, Jin Hyun Cho1, Young Hye Ko2, Won Seog Kim1 |
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| 임신과 동반된 원발성 종격동 거대 B세포 림프종에서 Rituximab 치료 |
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김은경1, 김석진1, 박성범1, 조진현1, 고영혜2, 김원석1 |
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| Abstract |
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A 33-year-old woman developed primary mediastinal large B-cell lymphoma (PMLBCL) during the second trimester of pregnancy. She was immediately treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP). After the third cycle of R-CHOP, she delivered a healthy baby by Caesarian section. She was in complete response after she finished all courses of treatment, and the rituximab-containing chemotherapy during pregnancy induced no adverse effect in the fetus. Thus, R-CHOP appears to be an effective, safe treatment option for PMLBCL encountered during the second and third trimesters of pregnancy. To our knowledge, this is the first report of the use of rituximab plus CHOP in a pregnant woman in Korea. |
| Key Words:
Lymphoma, Non-Hodgkin; Therapy; Pregnancy; Rituximab |
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