A Case of Renal Angiomyolipoma with Lymph Node-Associated Elevation of Tumor Markers

Korean J Med > Volume 80(2); 2011 > Article

Original Article

The Korean Journal of Medicine 2011;80(2):287-294.

A Case of Renal Angiomyolipoma with Lymph Node-Associated Elevation of Tumor Markers

Yu-Ah Hong1, Hyung Wook Kim1, Der-Sheng Sun1, Hae Mi Lee1, Jin Young Yoo2, Hoon-Kyo Kim1, Byoung Yong Shim1

종양표지자의 상승을 동반한 국소 림프절 침범 신혈관근지방종 1예

홍유아1, 김형욱1, 손덕승1, 이해미1, 유진영2, 김훈교1, 심병용1

Abstract

Angiomyolipoma is a rare, benign, mesenchymal hamartomatous neoplasm consisting of a mixture of adipose tissue, smooth muscle cells, and anomalous blood vessels. The kidney is a common origin site, but extrarenal angiomyolipoma has been reported. Simultaneous involvement of the kidney and regional lymph nodes is uncommon, and may be confused with a metastatic malignant lymph node. Lymph node involvement in angiomyolipoma represents a multifocal invasion of the tumor, rather than metastatic disease. Tumor markers usually associate with malignancy but they have sometimes been detected in benign conditions. We report a case of bilateral renal angiomyolipoma with tuberous sclerosis simultaneously involving regional lymph nodes confused with metastatic malignant lymph node enlargement due to associated elevation of serum tumor markers.

Key Words: Tumor markers, biological; Angiomyolipoma; Lymph nodes; Tuberous sclerosis