A Large Neuroendocrine Tumor of the Major Duodenal Papilla Removed by Endoscopic Papillectomy |
Seung-Hyeon Bae1, Jin Yong Kim1, Chang Lae Kim1, Young Kwon Choi1, Bo Mi Shin1, Seung-Mo Hong2, Myung-Hwan Kim1 |
1Departments of 1Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 2Departments of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea |
내시경 유두절제술로 제거한 거대 십이지장 주유두의 신경내분비종양 |
배승현1, 김진용1, 김창래1, 최영권1, 신보미1, 홍승모2, 김명환1 |
1울산대학교 의과대학 서울아산병원 내과 2울산대학교 의과대학 서울아산병원 병리과 |
Correspondence:
Myung-Hwan Kim, Tel: +82-2-3010-3183, Fax: +82-2-3010-0824, Email: mhkim@amc.seoul.kr |
Received: 17 April 2013 • Revised: 23 April 2013 • Accepted: 9 May 2013 |
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits
unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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Abstract |
Neuroendocrine tumors (NET) of the major duodenal papilla are rare and the natural history of this disease is not clear. We experienced a case in a 31-year-old male. Duodenoscopy revealed an enlarged major duodenal papilla with central umbilication and nodularity. Endoscopic ultrasonography (EUS) demonstrated a 3-cm hypoechoic mass that was confined to the submucosa. A biopsy led to the diagnosis of a grade 1 NET. The patient refused surgery, so we performed an endoscopic papillectomy. The tumor was removed completely. The resected specimen confirmed the diagnosis of a well-differentiated NET and all resection margins were negative. Surgical resection is currently considered to be the gold standard for the treatment of a large NET of the major duodenal papilla; however, endoscopic resection is a possible treatment modality for patients at high surgical risk or who are reluctant to undergo surgery. (Korean J Med 2014;86:319-324) |
Key Words:
Neuroendocrine tumors; Major duodenal papilla |
주제어:
신경내분비종양; 십이지장 주유두 |
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