Korean J Med > Volume 87(5); 2014 > Article
The Korean Journal of Medicine 2014;87(5):619-624.
Published online November 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.5.619   
Polycythemia Vera Presenting with Generalized Chorea: A Case Report and Review of the Literature
Sun Woong Kim1, Hyung Min Yu1, Yoon Jeong Lee1, Hee Jin Kim2, Mina Hur3, Hong Ghi Lee1
1Departments of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
2Departments of Neurology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
3Departments of Laboratoy Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
무도병을 주소로 내원한 진성적혈구증가증 1예
김선웅1, 유형민1, 이윤정1, 김희진2, 허미나3, 이홍기1
1건국대학교 의학전문대학원 건국대학교병원 내과
2건국대학교 의학전문대학원 건국대학교병원 신경과
3건국대학교 의학전문대학원 건국대학교병원 진단검사의학과
Correspondence: 
Hong Ghi Lee, Tel: +82-2-2030-7538, Fax: +82-2-2030-7748, Email: mlee@kuh.ac.kr
Received: 16 October 2013   • Revised: 30 December 2013   • Accepted: 15 January 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by erythrocytosis. Clinical symptoms can range in severity from headache and tinnitus to thrombohemorrhagic complications. Neurologic symptoms are common at the onset of polycythemia; however, chorea due to PV is a rare complication. We present the case of a 77-year-old female who was referred to our hospital because of choreic movement of the limbs, head and face. She was diagnosed with JAK2V617F mutation-positive PV. Her chorea was completely resolved by phlebotomy combined with hydroxyurea and aspirin.
Key Words: Polycythemia vera; Chorea disorders
주제어: 진성적혈구증가증; 무도병


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