| Nonerosive Reflux Disease |
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Tae Suk Kim, Sung Chul Park, Sung Joon Lee |
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Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea. |
| 비미란성 역류 질환 |
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김태석, 박성철, 이성준 |
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강원대학교 의학전문대학원 내과학교실 |
Correspondence:
Sung Joon Lee, Tel: +82-33-258-2405, Fax: +82-33-258-2404, Email: joon617@kangwon.ac.kr
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits
unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Abstract |
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Nonerosive reflux disease (NERD) is a distinct presentation of gastroesophageal reflux disease (GERD). NERD is commonly defined as the presence of classical GERD symptoms in the absence of esophageal mucosal erosions/breaks on upper endoscopy. Within the spectrum of GERD, the pathophysiological and clinical characteristics distinguishing NERD and erosive esophagitis remain a matter for debate. Recent research on NERD has focused on understanding the pathophysiology and natural history. Given the increased incidence of NERD in Korea, we reviewed the concept of NERD and its relationship to GERD and functional gastrointestinal disorders. |
| Key Words:
Nonerosive reflux disease; Gastroesophageal reflux disease; Heartburn |
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