A case of cyclosporine-induced blindness and coma after allogenic hematopoietic stem cell transplantation

Korean J Med > Volume 72(2); 2007 > Article

Original Article

The Korean Journal of Medicine 2007;72(2):284-288.

A case of cyclosporine-induced blindness and coma after allogenic hematopoietic stem cell transplantation

고려대학교 의과대학 내과학교실

증례 : 동종골수이식 후의 Cyclosporin에 의한 실명과 혼수 1예

최주현

Abstract

While nephrotoxicity and hypertension are the most common complications of cyclosporine use, 25～59% of transplant patients have also experienced cyclosporine induced neurotoxicity. However, the mechanism of cyclosporine-induced cortical blindness and coma remain poorly understood. The neurotoxicity usually improves when the use of cyclosporine is reduced or discontinued. However, irreversible results have been reported on rare occasion. We report here on a case of cyclosporine-induced blindness and coma after allogenic hematopoietic stem cell transplantation.(Korean J Med 72:S284-S288, 2007) Key Words : Cyclosporine, Neurotoxicity, Hematopoietic Stem Cell Transplantation

Key Words: Cyclosporine, Neurotoxicity, Hematopoietic Stem Cell Transplantation