Korean J Med > Volume 77(5); 2009 > Article
The Korean Journal of Medicine 2009;77(5):1222-1225.
A fatal case of colchicine intoxication with a “non-lethal” dose
Hyun Hee Na, So Young Jo, Myung Ok Kwak, Tsung Pei Chuan, Haeng Il Koh
소량의 Colchicine 음독 후 발생한 사망 1예
나현희·조소영·곽명옥·총배천·고행일, So Young Jo, Myung Ok Kwak, Tsung Pei Chuan, Haeng Il Koh
Abstract
In rheumatology, colchicine is used in the treatment of gout and Behçet’s syndrome. Colchicine intoxication, although rare, can cause symptoms ranging from mild gastrointestinal complaints to severe toxic conditions resulting in death. A 59-year-old woman visited the emergency department after ingesting 18 mg colchicine (30 tablets) 22 hours earlier. She complained of abdominal pain, vomiting, and diarrhea. We treated her conservatively and admitted her to the intensive care unit. Sixty-two hours after ingesting the colchicine, she complained of chest discomfort and dyspnea, and developed cardiac arrest immediately thereafter. Despite cardiopulmonary resuscitation, she died 68 hours after ingesting the colchicine. (Korean J Med 77:S1222-S1225, 2009)
Key Words: Colchicine; Drug toxicity


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