| A fatal case of colchicine intoxication with a “non-lethal” dose |
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Hyun Hee Na, So Young Jo, Myung Ok Kwak, Tsung Pei Chuan, Haeng Il Koh |
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| 소량의 Colchicine 음독 후 발생한 사망 1예 |
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나현희·조소영·곽명옥·총배천·고행일, So Young Jo, Myung Ok Kwak, Tsung Pei Chuan, Haeng Il Koh |
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| Abstract |
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In rheumatology, colchicine is used in the treatment of gout and Behçet’s syndrome. Colchicine intoxication, although rare, can
cause symptoms ranging from mild gastrointestinal complaints to severe toxic conditions resulting in death. A 59-year-old woman
visited the emergency department after ingesting 18 mg colchicine (30 tablets) 22 hours earlier. She complained of abdominal pain,
vomiting, and diarrhea. We treated her conservatively and admitted her to the intensive care unit. Sixty-two hours after ingesting the
colchicine, she complained of chest discomfort and dyspnea, and developed cardiac arrest immediately thereafter. Despite cardiopulmonary
resuscitation, she died 68 hours after ingesting the colchicine. (Korean J Med 77:S1222-S1225, 2009) |
| Key Words:
Colchicine; Drug toxicity |
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