A case of sarcoidosis presenting with multiple papules,hypercalcemia, and renal failure

Bo Young Min,; Won Hyeong Park,; Dae-Geun Song,; Tae Gyun Kim,; Hyun Gyung Park,; Beom Kim,; Yong Mee Cho,

Korean J Med > Volume 77(5); 2009 > Article

Original Article

The Korean Journal of Medicine 2009;77(5):1226-1230.

A case of sarcoidosis presenting with multiple papules,hypercalcemia, and renal failure

Bo Young Min, Won Hyeong Park, Dae-Geun Song, Tae Gyun Kim, Hyun Gyung Park, Beom Kim, Yong Mee Cho

피부병변과 고칼슘혈증, 신부전으로 발현한 유육종증 1예

민보영·박원형·송대근·김태균·박현경·김 범·조영미, Won Hyeong Park, Dae-Geun Song, Tae Gyun Kim, Hyun Gyung Park, Beom Kim, Yong Mee Cho

Abstract

Sarcoidosis is a granulomatous inflammatory disorder of unknown etiology. It can involve any organ and present in various clinical forms, but renal involvement is very unusual. We report on a 68-year-old man with renal sarcoidosis. He presented with unexplained renal impairment, hypercalcemia, and multiple light brown papules on the buttock and lower extremities. Non-caseating granulomas and interstitial nephritis were revealed in skin and kidney biopsies. The serum creatinine, hypercalcemia, and skin lesions rapidly improved on high-dose steroid therapy. One year later, the serum calcium level was normal, and serum creatinine was 1.3 mg/dL. (Korean J Med 77:S1226-S1230, 2009)

Key Words: Renal sarcoidosis; Renal failure; Hypercalcemia