A Case of Pulmonary Amyloidosis Mimicking Lymphangitic Lung Carcinomatosis

Shin, Beomsu; Ko, Jaehoon; Lee, Seong Soo; Lim, Kyung-Suk; Han, Joung Ho; Chung, Man Pyo; Jeong, Byeong-Ho

doi:2014.86.3.339

Korean J Med > Volume 86(3); 2014 > Article

Case Report

The Korean Journal of Medicine 2014;86(3):339-342.
Published online March 3, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.3.339

A Case of Pulmonary Amyloidosis Mimicking Lymphangitic Lung Carcinomatosis

Beomsu Shin¹, Jaehoon Ko¹, Seong Soo Lee¹, Kyung-Suk Lim¹, Joung Ho Han², Man Pyo Chung³, Byeong-Ho Jeong³

¹Departments of Internal Medicine, Departments of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
²Departments of Pathology, Departments of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
³Division of Pulmonary and Critical Care Medicine, Departments of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

림프관성 폐 암종증으로 오인된 폐 아밀로이드증 1예

신범수¹, 고재훈¹, 이성수¹, 임경숙¹, 한정호², 정만표³, 정병호³

^¹성균관대학교 의과대학 삼성서울병원 내과
^²성균관대학교 의과대학 삼성서울병원 병리과
^³성균관대학교 의과대학 삼성서울병원 호흡기내과

Correspondence:
Byeong-Ho Jeong, Tel: +82-2-3410-3429, Fax: +82-2-3410-3849, Email: bh82.jeong@samsung.com

Received: 22 August 2013 • Revised: 9 September 2013 • Accepted: 12 September 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Amyloidosis is defined by tissue deposits of amyloid, which cause both functional and structural damage to organs. Three histopathological types of pulmonary amyloidosis have been described: tracheobronchial, nodular parenchymal, and diffuse parenchymal or alveolar septal types. Diffuse alveolar septal involvement of the lung is a rare form of primary pulmonary amyloidosis, with radiological features similar to those of pulmonary edema, pulmonary fibrosis, and lymphangitic carcinomatosis. Therefore, it is always challenging to diagnose alveolar septal involvement of pulmonary amyloidosis. Here, we report a case of alveolar septal involvement of pulmonary amyloidosis mimicking lymphangitic carcinomatosis, which was diagnosed from a transbronchial lung biopsy. (Korean J Med 2014;86:339-342)

Key Words: Amyloidosis; Lung; Multiple myeloma; Lymphatic metastasis

주제어: 아밀로이드증; 폐; 다발성골수종; 림프관성 암종증