Korean J Med > Volume 87(6); 2014 > Article
The Korean Journal of Medicine 2014;87(6):675-685.
Published online December 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.6.675   
Ischemia-guided Revascularization for Stable Ischemic Heart Disease
Young-Hak Kim
Division of Cardiology, Department of Internal Medicine, Seoul Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
안정형 협심증 환자에서 허혈에 기반한 치료법
김영학
울산대학교 의과대학 서울아산병원 심장내과
Correspondence: 
Young-Hak Kim, Tel: +82-2-3010-3955, Fax: +82-2-486-5918, Email: mdyhkim@amc.seoul.kr
Abstract
Current evidence and guidelines support the strategy of ischemia-guided revascularization for treatment of patients with stable coronary symptoms. However, anatomical stenosis is often targeted in revascularization treatment using percutaneous coronary intervention or coronary artery bypass surgery without seriously considering objective evidence of myocardial ischemia. Angiographic complete revascularization was traditionally considered to be an ideal objective of revascularization treatment, particularly for patients with multivessel disease. However, recent observational studies have contradicted the concept of angiographic complete revascularization and have, instead, supported the benefits of ischemia-guided selective revascularization based on noninvasive and invasive functional evaluation for detection of ischemia-producing coronary lesions. No trials have been specifically designed to assess the relative benefits of either strategy. Therefore, the present review explores current concepts of the strengths and weaknesses of anatomical versus functional revascularization.
Key Words: Coronary artery disease; Stent; Bypass graft; Ischemia


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