Korean J Med > Volume 87(6); 2014 > Article
The Korean Journal of Medicine 2014;87(6):750-755.
Published online December 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.6.750   
Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma
SooJung Kim1, Won Cha Kang1, Sun Woong Kim1, Yoon Jeong Lee1, WookYoun Kim2, Hyun Jeong Kim3, Hong Ghi Lee1
1Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
2Department of Pathology Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
3Department of Laboratoy Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
성인 T세포 백혈병/림프종 환자에서 전이성 폐 석회화 1예
김수정1, 강원찬1, 김선웅1, 이윤정1, 김욱연2, 김현정3, 이홍기1
1건국대학교 의학전문대학원 건국대학교병원 내과
2건국대학교 의학전문대학원 건국대학교병원 병리과
3건국대학교 의학전문대학원 건국대학교병원 진단검사의학과
Correspondence: 
Hong Ghi Lee, Tel: +82-2-2030-7538, Fax: +82-2-2030-7748, Email: mlee@kuh.ac.kr
Received: 2 April 2014   • Revised: 1 May 2014   • Accepted: 16 June 2014
Abstract
Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using 99mTc-methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production.
Key Words: Adult T cell leukemia/lymphoma; Human T lymphotropic virus type 1; Calcification, pathologic


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