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Original Article
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Korean J Med. 2005;69(3):763-766.
- 증례 : Helicobacter pylori 제균 치료 후 발생한 Clostridium difficile 연관 대장염 1예
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유지원&#;황진혁&#;김진욱&#;김나영&#;이동호&#;정현채&#;송인성, , , , , ,
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- A case of Clostridium difficile-associated colitis after Helicobacter pylori eradication
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Ji Won Yoo, Jin-Hyeok Hwang, Jin Wook Kim, Na Young Kim, Dong Ho Lee, Hyun Chae Jung, In Sung Song
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Department of Medicine, Sungkyunkwan University School of Medicine
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- Abstract
- Helicobacter pylori infection of the gastric mucosa is related to chronic gastritis, peptic ulcer disease and the number of patients who are treated against this infection is increasing now. Although we think PPI-based triple therapies are safe, side effects can occur. Especially, Clostridium difficile-associated colitis was reported in other country after triple therapy, but there was no case report in Korea, We experienced a case of a 56 year-old male patient complains of severe diarrhea, who received triple therapy (rabeprazole 20 mg qd, clarithrmycin 500 mg bid, amoxicillin 1,000 mg bid) because of H.pylori associated chronic active gastritis.
In C.difficile toxin assay (ELISA), C.difficile toxin was detected,but pseudomembrane was not found in sigmoidoscopy. Symptoms were improved after 7-day treatment with oral metronidazole. We report a case of C.difficile-associated colitis after H. pylori eradication.(Korean J Med 69:S763-S766, 2005)
Keywords :Helicobacter pylori, Eradication, Clostridium difficile, Colitis, Korea
