The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2005;69(3):929-933.
증례 : 폐와 간을 동시에 침범한 랑게르한스 세포 조직구증 1예
오현숙&#;정윤호&#;윤여준&#;김윤정&#;서기현&#;나주옥&#;김용훈, , , , , ,
A case of Langerhans cell histiocytosis involving lung and liver
Hyun Suk Oh, Yoon Ho Chung, Yeo Jun Yoon, Yoon-Jung Kim, Ki Hyun Seo, Joo Ock Na, Yong Hoon Kim
Department of Medicine, Sungkyunkwan University School of Medicine


Abstract
A 43-year-old man presented with dry cough and right chest pain. Chest X-ray shows normal and chest CT scan revealed thin-walled cysts of various sizes and nodules in both upper lobe. Abdominal CT scan revealed multiple low attenuated nodules in liver and multiple abdominal lymph nodes enlargement. Liver biopsy was performed. Light microscopic examination revealed proliferation and infiltration of Langerhans cell. Immunohistochemically, Langerhans cells showed strong cytoplasmic staining with S-100 protein and CD1a. He was diagnosed Langerhans' cell histiocytosis involving lung and liver.(Korean J Med 69:S929-S933, 2005)

Keywords :Langerhans cell histiocytosis, Lung, Liver
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