The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2005;69(3):943-947.
증례 : Ciprofloxacin에 의해 유발된 중증 면역성혈소판감소증 1예
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A case of ciprofloxacin-induced severe immune thrombocytopenia
Sung-Ki Ahn, Hyun-Young Son, Ja Young Kim, Hyoung-Chul Oh, Jae Bum Jun, Jae-Pil Yun, Seong-Jun Choi
Department of Medicine, Sungkyunkwan University School of Medicine


Abstract
Ciprofloxacin is generally considered to be a safe drug with infrequent hematological side effects such as thrombocytopenia. Here, we report a case of severe immune thrombocytopenia associated with the use of ciprofloxacin. A 64-year-old man developed generalized purpura and severe epistaxis associated with severe thrombocytpenia that occurred after the use of ciprofloxacin. Thrombocytopenia persisted in spite of repeated platelet transfusion. After discontinuation of ciprofloxacin and the use of corticosteroid and immunoglobulin, his platelet count rapidly recovered to normal value and his bleeding symptoms disappeared.(Korean J Med 69:S943-S947, 2005)

Keywords :Ciprofloxacin, Thrombocytopenia
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