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Original Article
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Korean J Med. 2006;70(1):26-32.
- 원저 : 건강검진 수진자에서 비알콜성 지방간질환의 유병률 및 연관 인자들 (Original Articles : Prevalence and associated factors of nonalcoholic fatty Liver disease in the health screen examinees)
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서상혁, 이현웅, 박혜원, 장병국, 정우진, 박경식, 조광범, 황재석, 안성훈
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Sang Hyuck Seo, Hyun Woong Lee, Hye Won Park, Byoung Guk Jang, Woo Jin Chung, Kyung Sik Park, Kwang Bum Cho, Jae Seok Hwang, Sung Hoon Ahn
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부산대학교 의과대학 내과학교실
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- Abstract
- Background : Nonalcoholic fatty liver disease (NAFLD) is a kind of most common hepatic
disease having wide pathologic spectrum and has been increasingly recognized as an important
disorder because it may progress to end stage of liver disease. In spite of several foreign reports
about clinical aspects of NAFLD, there are not enough reports analyzing large group for long times
in Korea. We have examined the prevalence and associatd factors for NAFLD in health screen
examinees from January 1997 to June 2003.
Methods
: The results of 29,781 health screen examinees were analyzed retrospectively.
Prevalence of alcoholic and nonalcoholic fatty liver was computed and associating factors were
analyzed statistically.
Results
: Overall prevalence of NAFLD was 18.6% and higher in the groups of age over 50 years.
NAFLD was more preponderant in male. Age, body mass index, diabetes mellitus, hypercholesterolemia,
hypertriglyceridemia, and abnormal serum low density lipoprotein, high density lipoprotein,
ALT level were independently associated factors with presence of NAFLD in logistic regression
analysis.
Conclusions
: The prevalence of NAFLD and tendency of associated factors were similar to
Western world. To prevent development of this common hepatic disorder which may results in end
stage liver disease, prevention and control of obesity, diabetes, hyperlipidemia must be important.
(Korean J Med 70:26-32, 2006)
Key Words : Fatty Liver, Non-alcoholic, Prevalence
Keywords :Fatty Liver, Non-alcoholic, Prevalence
