The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2006;70(2):226-231.
증례 : AML1/ETO 양성 급성 골수성 백혈병 환자에서 동종 조혈모세포 이식 이후에 골수 외 재발된 2예 (Case Reports : Cases of extramedullary relapse after alloBMT in AML1/ETO positive AML)
이진국, 김미경, 송명준, 엄기성, 김희제, 민우성, 김춘추
Chin Kook Lee, Mee Kyoung Kim, Myung Jun Song, Ki Seong Eom, Hee Je Kim, Woo Sung Min, Chun Choo Kim
서울의대 내과


Abstract
The occurrence of granulocytic sarcoma as a pattern of relapse after allogenic bone marrow transplantation (allo-BMT) is rare. We report two AML1/ETO positive patients with granulocytic sarcoma as a pattern of relapse after allo-BMT. The first case is 39-year-old woman who had lower back pain without any abnormal peripheral blood exam. MRI showed a paraspinal mass, and the pathologic report was granulocytic sarcoma. The second case is 34-year-old woman who had breast humps without any abnormal peripheral blood exam. CT showed multiple breast masses, and the pathologic report was granulocytic sarcoma. We believe that this is the first cases report of extramedullary relapse after allo-BMT in AML1/ETO positive AML in Korea. These cases suggest that we should be aware of the possibility of an extramedullary relapse in bone marrow transplant recipients with AML1/ETO positive AML.(Korean J Med 70:226-231, 2006) Key Words : AML1/ETO, Relapsed AML, Bone marrow transplantation

Keywords :AML1/ETO, Relapsed AML, Bone marrow transplantation
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