The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2006;70(2):358-362.
증례 : 광범위한 피부괴사가 있는 Churg-Strauss 증후군에 동반된 폐혈전색전증
송주경
Case Reports : Extensive skin necrosis in Churg-Strauss syndrome with pulmonary thromboembolism
Ju Kyoung Song
한림의대 한강성심병원 내과


Abstract
Churg-Stauss syndrome (CSS) is a systemic vasculitis, characterized by asthma, blood and tissue eosionophilia and diffuse organ involvement. A 70-year-old woman with a 2-year history of bronchial asthma was admitted because of extensive hemorrhagic bullae and necrosis on both lower extremities, buttocks and trunk, tingling sensation on both lower legs. She showed eosinophilia, p-ANCA(+) and histopathologically leukocytoclastic vasculitits, peripheral mononeuropathy, chronic sinusitis. She experienced episodic syncope and dizziness in hospital days. Spiral CT of chest showed pulmonary thromboembolism.nShe was diagnosed as Churg-Stauss syndrome with pulmonary thromboembolism, received high dose prednisolone, cyclophosphamide, thrombolytic and anticoagulation therapy. And her clinical findings were improved.(Korean J Med 70:S358-S362, 2006) Key Words : Churg-Strauss syndrome, Hemorrhagic bullae, Cutaneous necrosis, Pulmonary thromboembolism

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