The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2006;71(1):75-79.
만성 설사와 저칼륨혈증으로 발현된 교원성 대장염 1예
백수정, , , , , ,
A case of collagenous colitis presented with chronic diarrhea and hypokalemia
Su Jung Baik, Yun Su Sim, Sung Ae Jung, Ki Nam Shim, Kwon Yoo, Il Hwan Moon, Woon Sup Han
한림의대 한강성심병원 내과


Abstract
Collagenous colitis is recognized as one of the causes of chronic diarrhea accompanied with autoimmune diseases. It is a disease associated with chronic watery diarrhea and typical histologic findings of a thick subepithelial collagenous deposit on biopsy. We experienced a 75-year-old man patient with chronic watery diarrhea and mild abdominal pain for 7 years. Physical examination, laboratory and radiologic studies were unremarkable except hypokalemia. Colonoscopy disclosed mucosal atrophy, loss of submucosal vessel and altered vascularity of terminal ileum, ascending colon. Colonoscopic biopsy revealed homogenous hyaline layered collagen deposition beneath the surface epithelium and Masson's trichrome stain showed collagen deposition. We report the case of collagenous colitis with a review of literature. Key Words : Collagenous colitis, Diarrhea

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