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Review
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Korean J Med. 2006;71(1):137-137.
- Gender Difference on Arterial Stiffness Presents after the Correction of Body Habitus in Patients with or without Coronary Artery Disease
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황선호, 김계훈, 정명호, 오춘순, 이수진, 김미애, 홍서나, 홍영준, 이상록, 김계훈, 김주한, 안영근, 조정관, 박종춘, 강정채, 박옥규
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전남대학교 의과대학 내과학교실
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- Abstract
- Background and Objectives
Arterial stiffness measured by pulse wave velocity (PWV) can be affected by body habitus. The aim of this study was to investigate the gender difference on arterial stiffness in patient with or without coronary artery. Methods: A total of 803 consecutive patients who planned to perform coronary angiography (CAG) were divided into two groups according to the results of CAG; group I (CAD group: 547 patients, 61.63¡¾10.40 years old, 369 males) and group II (No CAD group: 256 patients, 56.55¡¾11.28 years old, 176 males). PWV at different arterial sites were measured using VP-2000 (Colins, Japan) before CAG and gender differences were analyzed. Results: Heart-carotid (hcPWV) (839.33¡¾230.42 vs. 772.89¡¾308.22msec, p=0.001) and brachial-ankle PWV (baPWV) (1461.38¡¾334.81 vs. 1546.54¡¾339.93msec, p=0.001) were significantly different in males than in females. However, heart-femoral (hfPWV) (1009.38¡¾234.83 vs. 981.79¡¾252.08msec, p=0.129) and femoral-ankle PWV (faPWV) (1022.90¡¾1048.06 vs. 1048.06¡¾187.90msec, p=0.059) were not different between the sex. In group I, femoral-ankle PWV (1012.24¡¾178.01 vs. 1060.47¡¾189.99msec), brachial-ankle PWV (1471.78¡¾361.01 vs 1610.10¡¾340.54msec), weight (68.55¡¾9.57 vs. 58.49¡¾7.97 kg, p<0.001), and height (167.10¡¾5.71 vs. 153.05cm, p<0.001) were significantly different. However, heart-femoral PWV (1028.72¡¾237.99 vs. 1042.38¡¾267.25msec, p=0.56) were not different between the sex. In group II, heart-femoral PWV (959.29¡¾218.50 vs 895.93¡¾200.55msec, p<0.001), weigh (72.4¡¾10.3 vs. 60.6¡¾8.3 kg, p<0.001), and height (168.4¡¾5.9 vs. 155¡¾5.8 cm, p<0.001) were significantly different, but heart-carotid PWV (806.50¡¾228.2 vs. 779.17¡¾428.87msec, p=0.54), brachial-ankle PWV (1434.88¡¾248.90 vs. 1451.01¡¾317.12) and femoral-ankle PWV (1050.66¡¾162.45 vs. 1029¡¾184.06msec, p=0.34) were not different between the sex. Conclusion: There is a significant gender difference of arterial stiffness measured by PWV in patients with or without coronary artery disease in spite of correction for height and weight.
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