The Korean Journal of Internal Medicine

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Korean J Med. 2006;71(1):283-283.
A Novel Technique for assessing myocardial performance index in atrial fibrillation:Dual pulse wave Doppler method.
김성해&#;이상철&#;전은석&#;이상훈&#;홍경표&#;박정의&#;박승우
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A Novel Technique for assessing myocardial performance index in atrial fibrillation:Dual pulse wave Doppler method.
1Department of Internal Medicine, Hanyang University College of Medicine, Seoul; 2Department of Life Science, Postech Biotech Center, Pohang University of Science and Technology, Pohang, Korea


Abstract
Background : The myocardial performance index(MPI) is well known parameter for evaluating global systolic function. But it cannot be calculated in atrial fibrillation(AF) either by pulsed wave(PW) doppler method nor by tissue Doppler method because of ambiguous or absence of A and a wave. Objective : We developed Dual pulsed wave doppler method which enabled us to obtain both mitral and aortic PW at the same cardiac cycle including surface ECG from apical 5 chamber view. We planned to determine this method are feasible and reliable in assessing MPI in AF Methods : The isovolumetric contraction time (ICT) was measured from onset of QRS on surface ECG to the onset of aortic PW, the ejection time (ET) from the onset to the end of aortic PW, and the isovolumetric relaxation time (IRT) from the end of aortic PW to the onset of mitral PW. We caculated MPI repeatedly in 11 patients with AF up to 8 cardiac cycles Results : We were able to calculate clearly MPI in all patients. Intraclass correlation coefficient(ICC) for the MPI was 0.84 (95% confidence interval (95% CI), 0.71-0.94), for ET 0.90 (95% CI, 0.80-0.97), for ICT 0.88(95% CI, 0.76-0.96) and for IRT 0.73(95% CI, 0.53-0.90); all p value < 0.01. But heart rate showed poor agreement which reflect variation of cardiac cycle length in AF(ICC= 0.47 (95% CI, 0.24-0.74)). Conclusion : Dual PW doppler method enabled us to calculate the MPI even on AF. MPI obtained from this method may help to assess on systolic function in AF.

Keywords :
hanmi ckdpharm. AMGEN
Memo patch yungjin daewoongbio

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