The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2006;71(3):309-315.
증례:후신경모세포종에 합병된 이소성 부신피질자극 호르몬 증후군 1예
구보경, , , , , ,
A case of ectopic adrenocorticotropic hormone syndrome with olfactory neuroblastoma
Bo Kyung Koo, Yun Hyi Ku, Jin Taek Kim, Hong Il Kim, You Jin Lee, Young Min Cho, Seong Yeon Kim
고려대학교 의과대학 내과학교실


Abstract
We here present the case of a 37-year-old woman who suffered from adrenocorticotrophic hormone (ACTH)-dependent Cushing's syndrome due to an olfactory neuroblastoma. The patient's clinical course was complicated by co-infection with cytomegalovirus and Pneumocystis jirovechi, which improved with appropriate antimicrobial therapy and suppression of endogenous steroidogenesis with ketoconazole and octreotide. Radiation to the mass in the nasal cavity resulted in reduction of tumor size and remission of the Cushing's syndrome. This is the first report of the ectopic ACTH syndrome resulting from olfactory neuroblastoma in Korea.(Korean J Med 71:309-315, 2006) Key Words : Neuroblastoma, Olfactory, ACTH Syndrome, Ectopic

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