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Original Article
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Korean J Med. 2006;71(5):535-542.
- 원저:섬유근통증 환자에서의 혈중 지질 농도
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이정남, , , , , ,
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- Serum lipid profile in patients with fibromyalgia
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Jung Nam Lee, San Kim, Jong Ryul Park, Jin Ho Lee, Chun Kwan Lee, Jae Hoon Jeong, Ji Hyun Lee
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고려대학교 의과대학 내과학교실
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- Abstract
- Background : Fibromyalgia syndrome (FMS) is a chronic musculoskeletal disorder that’s
characterized by widespread bodily pain, chronic fatigue, irritable bowel syndrome and increased
tenderness at specific anatomic sites. This study was undertaken to compare the serum lipid profiles
in patients with FMS and the healthy controls, and we also wanted to investigate relationship
between the serum lipid levels and the symptoms in FMS patients
Methods
: Fifty three patients who visited Maryknoll Hospital between March 2001 and March
2005 were included; they were compared with 53 age & gender‐matched healthy adults. We
assessed the serum lipid profile of the FMS patients in terms of the tender points, the Korean
Fibromyalgia Impact Questionnaire (KFIQ) scores and the Korean Center for Epidemiologic Studies
Depression (KCES-D) scores.
Results
: Total cholesterol (208.9±38.5 vs 194.2±37.1, respectively, p=0.047) and LDLcholesterol
(low density lipoprotein cholesterol, 121.9±31.0 vs 109.3±32.2, respectively, p=0.043)
were significantly higher in the FMS patients than in the controls. The tender points and KCES D
scores were inversely influenced by the total cholesterol, and there was a statistically significant
difference. The KFIQ score was inversely influenced with the lipid profile, but there was no
statistically significant difference.
Conclusions
: The results showed significant differences in the lipid levels of FMS patients and
the controls. More extensive investigation of the lipid levels is required to determine whether the lipid
levels are associated with FMS.(Korean J Med 71:535-542, 2006)
Key Words : Fibromyalgia, Lipid profile, Cholesterol
Keywords :
