The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2006;71(3):1153-1156.
증례 : Cimetidine 주사제에 의한 혈관부종 1예
심윤수&#;류정화&#;변건우&#;윤수진&#;박창한&#;조영주, , , , ,
Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea2
A case of angioedema induced by an injection of cimetidine
, , , , ,
건국대학교 의과대학 내과학교실, 가톨릭대학교 의과대학 내과학교실2


Abstract
Cimetidine is well-tolerated H2-receptor antagonist. The most common adverse effects of cimetidine are diarrhea, nausea, headache, dizziness, rash, gynecomastia and myalgia. Only a few hypersensitivity reactions to cimetidine have been reported. We report here on a 22 year-old woman who suffered from edema of the lip, hand and foot, and chest tightness after an intravenous injection of cimetidine. The angioedema was improved with antihistamine and systemic steroid. The intradermal skin test to injecting cimetidine was positive. The positive skin test suggests that this rare conditionmay be due to type 1 hypersensitivity.(Korean J Med 71:S1153-S1156, 2006)

Keywords :Cimetidine, Angioedema, Drug hypersensitivity
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