The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2007;72(1):79-84.
증례: 다발성근염과 만성 B형 간염에 병발한 혼합 간세포-담관상피암종 1예
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A case of combined hepatocellular-chloangiocarcinoma associated with polymyositis and chronic hepatitis B virus infection
Hey Jin Jeong, Seong Hun Kim, Se In Kim, In Hee Kim, Woo Sung Moon, Seung Ok Lee, Dae Ghon Kim
고려대학교 의과대학 내과학교실


Abstract
Polymyositis is characterized by symmetrical proximal muscle weakness, nonsuppurative inflammation of striated skeletal muscle, an elevation of muscle enzymes, and abnormality of electromyographical changes, but its pathogenesis is not clear. In recent years, there has been an increased awareness of the association of malignant tumors with this disorder. Still, the relationship between polymyositis and a malignant tumor remain obscure. Some researchers have suggested that the cause of polymyositis may be due to an autoimmune response induced by aviral infection. However, a chronic hepatitis B virus infection associated with polymyositis is very rare. We present in this report a rare case of combined hepatocellular-cholangiocarcinoma associated with polymyositis and chronic hepatitis B virus infection.(Korean J Med 72:79-84, 2007) Key Words : Polymyositis, Chronic hepatitis B, Hepatocellular carcinoma

Keywords :Polymyositis, Chronic hepatitis B, Hepatocellular carcinoma
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