The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2007;72(6):673-678.
증례 : 폐암에 동반되어 동맥 혈전색전증으로 발현된 Trousseau 증후군 1예
조영재, , , , , ,
A case of trousseaus syndrome associated with adenocarcinoma of the lung
Young Jae Cho, Hee Joung Kim, Ji Eun Lee, Joon Sung Joh, Sung Koo Han, Young Soo Shim, Chul Gyu Yoo
고려대학교 의과대학 내과학교실


Abstract
In 1865, Armand Trousseau recognized the first relationship between a neoplastic disease and a thromboembolic disorder. Since then, many cases have been reported and have been termed as Trousseau's syndrome. One mechanism of hypercoagulability was considered to be the activation of coagulation systems by a tissue factor secreted by neoplastic cells, but accurate pathophysiology still remains unknown. We report a case of a multiple and recurrent thromboembolism in a patient with adenocarcinoma of the lung. A woman aged 68 years with an acute thromboembolism at her right distal calf artery was diagnosed as having adenocarcinoma of the lung. She underwent a thromboembolectomy two times, but had to receive surgery for a below knee amputation. Multiple and recurrent thromboembolic events then attacked her cerebral and coronary arteries, which led to cerebral and myocardial infarctions. She expired by a progression of the adenocarcinoma of the lung after about six months.(Korean J Med 72:673-678, 2007) Key Words : Adenocarcinoma, Lung, Trousseau's syndrome

Keywords :Adenocarcinoma, Lung, Trousseau's syndrome
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