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Original Article
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Korean J Med. 2007;73(4):432-437.
- 증례 : 뇌하수체 거대선종 수술 후 발생한 뇌성염분소실
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송탁호.라성수.방창석.이상석.강하얀.김희진.이상구, , , , , ,
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- Cerebral salt wasting following pituitary surgery for macroadenoma
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Tak Ho Song, Sung Soo La, Chang Seok Bang, Sang Seok Lee, Ha Yan Kang, Hee Jin Kim, Sang Koo Lee
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성균관대학교 의과대학 삼성서울병원 심장혈관센터 순환기내과
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- Abstract
- The central nervous system (CNS) has important roles in the regulation of sodium and water homeostasis, so the risk
of hyponatremia is increased for patients with neurological disorders. Cerebral salt wasting (CSW) is a syndrome that
is characterized by hyponatremia and extracellular volume contraction, and these problems are caused by natriuresis and
the concomitant polyuria in patient with intracranial disease. It is critical to differentiate CSW from syndrome of
inappropriate secretion of antidiuretic hormone (SIADH) for patients with hyponatremia and after they experience
cerebral insults. This is because fluid restriction is the treatment of choice for SIADH and administration of isotonic or
hypertonic saline is important for treating CSW. We report here on a case of CSW following trassphenoidal surgery for
pituitary tumor in a 67-year-old man with nonfunctioning pituitary macroadenoma. Hyposmotic hyponatremia, increased
urine output and signs of dehydration developed postoperatively, and the patient was managed by water and salt
supplementation.(Korean J Med 73:432-437, 2007)
Keywords :Hyponatremia, Cerebral salt wasting, Syndrome of inappropriate secretion of antidiuretic hormone,
