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Original Article
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Korean J Med. 2007;73(4):438-442.
- 증례 : 진성다혈구증에 병발된 미세변화형 신증 1예
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한대희.조 성.김성록.김윤영.강구현.임상우.김정훈, , , , , ,
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- A case of minimal change nephrotic syndrome with polycythemia vera
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Dae Hui Han, Seung Cho, Sung Rok Kim, Yun Young Kim, Gu Hyun Kang, Sang Woo Yim, Jung Hun Kim
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경희대학교 의과대학 순환기내과학교실
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- Abstract
- The cause of secondary polycythemia is known to be renal diseases such as renal tumors, renal cysts, hydronephrosis,
renal artery stenosis, renal transplantation and Bartter's syndrome. Yet this disease rarely reported in conjunction with
nephrotic syndrome, nephrosclerosis, pyelonephritis or chronic glomerulonephritis. There are only rare reports of
glomerulonephritis with polycythemia vera. We report here on a case of a minimal change nephrotic syndrome with
polycythemia vera. A 60-year-old man visited our hospital due to his elevated hemoglobin level and proteinuria and his
elevated neuron specific enolase. The blood hemoglobin level was 22.4 g/dL. The blood level of neuron specific enolase
was 36.7 ng/mL. The bone marrow aspirate showed hypercellularity and panmyelosis. Electron microscopy showed
diffuse effacement of the epithelial foot processes and microvillous transformation of the foot processes. Treatment was
done by performing phlebotomy and administering hydroxyurea. There was decreased urinary protein and normalization
of the hemoglobin level following treatment with phlebotomy and hydroxyurea.(Korean J Med 73:438-442, 2007)
Keywords :Proteinuria, Hemoglobin
