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Original Article
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Korean J Med. 2007;73(3):101-105.
- 증례 : 미세변화 신증후군이 첫 증상으로 발현된 피부근염 1
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서준혁&#;조민재&#;유정현&#;이동욱&#;김용섭&#;이찬우&#;오동호, , , , , ,
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- A case of minimal change nephropathy as a primary manifestation of dermatomyositis
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Jun Hyuk Seo, Min Jae Jo, Jung Hyun You, Dong Wok Lee, Yong Sup Kim, Chan Woo Lee, Dong Ho Oh
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경희대학교 의과대학 순환기내과학교실
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- Abstract
- Dermatomyositis is a disease characterized by non-pyogenic inflammation of the skin and muscles in which the
tissues and cells are damaged by pathogenic autoantibodies and immune complexes. Unlike interstitial lung disease,
which is reported to occur in 15～30% of patients with dermatomyositis and polymyositis, renal lesions are rarely present
with dermatomyositis and polymyositis. Only a few isolated cases of dermatomyositis associated glomerulonephritis have
been reported to date. Therefore, we present a case of nephropathy as a primary manifestation of dermatomyositis. A
32-year-old female patient was admitted for renal biopsy due to facial edema and proteinuria. Renal biopsy showed the
findings of minimal change nephropathy. Heliotroph rash and Gottron’s papules were noted on the physical examination.
The findings of EMG, MRI of the thigh and thigh muscle biopsy were compatible with those of dermatomyositis. Minimal
change nephropathy is a rare manifestation in patients with dermatomyositis, and we report this case with a review of
literature.(Korean J Med 73:S1101-S1105, 2007)
Keywords :Dermatomyositis, Nephrotic syndrome
