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Original Article
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Korean J Med. 2008;74(1):127-130.
- 증례 : 항사구체 기저막 항체 및 ANCA 양성인 신증후출혈열 1예
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신호식, 박찬호, 이정규
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- A case of hemorrhagic fever with renal syndrome associated with antiglomerular sement membrane antibody and antineutrophil cytoplasmic antibody
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Ho Sik Shin, Chan Ho Park, Jung Gyu Lee
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한림대학교 의과대학 춘천성심병원 내과, 산부인과1
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- Abstract
- Hemorrhagic fever with renal syndrome (HFRS), caused by several types of hantavirus (i.e., Hantaan, Dobrava, Seoul, and Puumala), is characterized by fever of acute onset and acute renal insufficiency. The mechanism for renal injury in HFRS remains unclear. Renal biopsy specimens from patients with HFRS caused by Hantaan virus have revealed viral glycoproteins in renal tubular cells. This may suggest that hantaviruses directly contribute to acute renal failure. However, immune mechanisms have been proposed. In this paper, we report a case of HFRS associated with antiglomerular basement membrane antibody and antineutrophil cytoplasmic antibody.
Keywords :Hemorrhagic fever with renal syndrome, Antiglomerular basement membrane antibody, Antineutrophil cytoplasmic antibody
