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Original Article
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Korean J Med. 2008;75(1):122-127.
- 증례 : 급성신부전과 현미경적 신석회화증을 동반한 부갑상선암 1예
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최윤정.안원석.강도영.나서희.김성은.김덕규.김기현, , , , , ,
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- A case of parathyroid carcinoma with acute renal failure and microscopic nephrocalcinosis
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Yun Jung Choi, Won Suk An, Do Young Kang, Seo Hee Rha, Seong Eun Kim, Duk Kyu Kim, Ki Hyun Kim
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성균관대학교 의과대학 삼성서울병원 심장혈관센터 순환기내과
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- Abstract
- Parathyroid carcinoma is a very rare disease in patients with primary hyperparathyroidism. Renal impairment and bone disease in the case of parathyroid carcinoma is common due to hypercalcemia. Renal diseases, including nephrocalcinosis, nephrolithiasis, and renal failure are frequent compared with those of benign parathyroid tumors. Nephrocalcinosis is a disorder of increased calcium content and deposition within renal parenchyma. Most cases reporting parathyroid carcinoma have shown medullary calcinosis on radiologic images, but there has been no definitive report of microscopic nephrocalcinosis which does not have a positive radiologic finding. In the case reported herein, a 50-year-old woman had experienced general weakness and a decline in vision. She had hypercalcemia and acute renal failure and the renal biopsy revealed nephrocalcinosis. The PTH level was elevated (940.47 pg/mL) and the parathyroid tumor was localized based on several radiologic findings. Capsular invasion was noted at the time right parathyroidectomy, indicative of parathyroid carcinoma, thus we carried out ipsilateral thyroidectomy. Hypercalcemia was improved after surgery, but renal function was not improved completely due to microscopic nephrocalcinosis. (Korean J Med 75:122-127, 2008)
Key Words : Parathyroid carcinoma; Microscopic nephrocalcinosis; Acute renal failure; Hypercalcemia
Keywords :Parathyroid carcinoma, Microscopic nephrocalcinosis, Acute renal failure, Hypercalcemia
