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Original Article
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Korean J Med. 2008;75(3):362-366.
- 증례: 재발된 그레이브스병 환자에서 항갑상샘약제 재투여 후 발생한 무과립구증 1예
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정귀홍&#;김성균&#;명대성&#;정진욱&#;조동혁&#;정동진&#;정민영, , , , , ,
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- Agranulocytosis due to secondary exposure to antithyroid drugs in a relapsed Graves' disease patient
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Gwi Hong Jeong, Seong Kyun Kim, Dae Seong Myung, Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
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경희대학교 의과대학 순환기내과학교실
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- Abstract
- Antithyroid drugs are the most common treatment modality for Graves' disease and are used for the treatment of relapsed Graves' disease in Korea. Agranulocytosis is a rare and severe complication of antithyroid drug therapy, and most cases occur within 3 month after drug treatment. Agranulocytosis can develop in patients who have relapsed Graves' disease and undergo a second course of antithyroid drugs with a prior uneventful course of drug therapy.
We report a case of antithyroid drug-induced agranulocytosis in a relapsed Graves' disease patient who had undergone prior uneventful antithyroid drug therapy. We also present a review of the relevant literature. (Korean J Med 75:362-366, 2008)
Keywords :Graves' Disease, Recurrence, Antithyroid agents, Agranulocytosis
