The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2008;75(4):459-462.
증례: 간경변 환자에서 발생한 마크로아밀라아제혈증과 마크로리파아제혈증 1예
임평숙 . 김소영 . 염동한 . 조은영 . 최창수 . 김학철 . 조지현, , , , , ,
Macroamylasemia and macrolipasemia in patient with alcoholic liver cirrhosis
Pyoung Suk Lim, So Young Kim, Dong Han Yeom, Eun Young Jo, Chang Soo Choi, Haak Cheoul Kim, Ji Hyun Cho
경희대학교 의과대학 순환기내과학교실


Abstract
Macroenzymes are high molecular weight complexes formed in the serum by self-polymerization or by association with other proteins. Macroenzymes are filtered with difficulty by normal renal glomeruli. Clinically, it is important to detect macroenzymes, because they frequently interfere with the interpretation of serum enzyme results, and as a result they can cause diagnostic and therapeutic errors. Macroamylasemia and macrolipasemia have been found to occur in apparently healthy humans, as well as in a variety of disease states, including liver disease, diabetes, cancer, malabsorption, and autoimmune disorders. We report a patient with alcoholic liver cirrhosis and macroamylasemia and macrolipasemia, the latter two of which were discovered using a screening test. (Korean J Med 75:459-462, 2008)

Keywords :Macroamylasemia, Macrolipasemia, Liver cirrhosis
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