The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2008;75(6):689-693.
대장내시경 전 처치 약제 Solin® 투여 후 발생한 고인산혈증 및 급성신부전 1예
박종원, 송재천, 임현철, 강병승, 배기선, 박효진, 하성규
A case of hyperphosphatemia and acute renal failure following the administration of solin® (oral sodium phosphate)
Jong Won Park, Jae Chun Song, Hyun Chul Lim, Byeung Seung Kang, Ki Sun Bae, Hyo Jin Park, Sung Kyu Ha
경희대학교 의과대학 순환기내과학교실


Abstract
Solin® (oral sodium phosphate) is a commonly used osmotic laxative solution that has replaced polyethylene glycol in bowel preparation for colonoscopy as it has equal or greater efficacy and patient compliance. However, its use has been associated with several cases of acute renal failure and electrolyte imbalance, especially hyperphosphatemia and hypocalcemia. Those at higher risk of complications are patients who are older and have intestinal obstruction, inflammatory bowel disease, renal failure, or congestive heart failure. We report the case of a 61-year-old woman presenting with paresthesia in both hands after using Solin® for bowel preparation for colonoscopy. The patient had hypocalcemia and hyperphosphatemia combined with acute renal failure. She recovered from the renal failure and electrolyte imbalance with intravenous hydration and treatment with phosphate-binding agents. (Korean J Med 75:689-693, 2008)

Keywords :Oral sodium phosphate, Acute renal failure, Hyperphosphatemia
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