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Original Article
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Korean J Med. 2008;75(3):877-880.
- 증례 : 인슐린 자가 면역성 증후군 1예
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김용성.박성우.원종철.박철영.김창준.김화목.최지훈, , , , , ,
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- A case of insulin autoimmune syndrome
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Yong Sung Kim, Sung Woo Park, Jong Chul Won, Cheol-Young Park, Chang Joon Kim, Hwa Mock Kim, Ji Hoon Choi
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- Abstract
- Hirata et al. first reported insulin autoimmune syndrome in 1970. This condition is characterized by spontaneous hypoglycemia with no evidence of exogenous insulin administration, a high total serum insulin, and the presence of a high titer of insulin antibodies. A healthy 60-year-old man suffered episodes of weakness, sweating, and spontaneous hypoglycemia in the late postprandial state. He was being treated with amoxicillin for upper respiratory tract infection. His laboratory findings showed a high titer of insulin antibody and high serum insulin level, but no evidence of an insulinoma in imaging studies. We treated him with prednisolone for 2 months. His insulin antibody titer decreased and no further hypoglycemic events were developed. We present this case with a review of the relevant literature. (Korean J Med 75:S877-S880, 2008)
Keywords :Insulin antibody, Fasting hypoglycemia, Sulfhydryl group, Insulin autoimmune syndrome
