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Original Article
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Korean J Med. 2008;75(3):889-893.
- 증례 : 하제 과다복용 후 발생한 증후성 고마그네슘혈증 1예
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곽진호.강건우.권정석.신영국.김명환.이인희.안기성, , , , , ,
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- Hypermagnesemia induced by massive cathartic ingestion
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Jin Ho Kwak, Gun Woo Kang, Jung Suk Kwon, Young Kook Shin, Myung Hwan Kim, In Hee Lee, Ki Sung Ahn
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- Abstract
- Hypermagnesemia is a rare laboratory finding and is easily neglected. Symptomatic hypermagnesemia is mainly iatrogenic, occurring after intravenous magnesium administration or the oral ingestion of magnesium-containing cathartics or antacids. The elderly and patients with bowel disorders or renal insufficiency are at high risk, and marked hypermagnesemia is a serious, often fatal condition in these patients. A 71-year-old man was referred to our hospital for hypotension, refractory to catecholamine. He had already received 21g of magnesium hydroxide orally for two days. He was lethargic, and his systolic blood pressure was less than 80 mmHg. The serum magnesium concentration was elevated to 5.85 mg/dL. On the sixth hospital day, his hypermagnesemia improved with intravenous calcium, inotropics, and saline infusion, but he remained in respiratory depression and ileus until the serum magnesium concentration was lowered to less than 2.2 mg/dL. Unfortunately, on the twelfth hospital day, he died from ventilatory-associated pneumonia and ventricular tachycardia. (Korean J Med 75:S889-S893, 2008)
Keywords :Magnesium, Magnesium hydroxide, Cathartic
