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Original Article
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Korean J Med. 2008;75(3):913-916.
- 증례 : 에이즈 환자에서 파르보바이러스 B19 감염으로 발생한 순수적혈구무형성증 1예
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이재훈.김의종.오명돈, ,
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- A case of pure red cell aplasia associated with parvovirus B19 infection in an AIDS patient
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Jae Hoon Lee, Eui Chong Kim, Myoung-don Oh
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- Abstract
- Persistent infection with parvovirus B19 is an important treatable cause of anemia in HIV-infected patients. The failure to produce neutralizing antibodies to parvovirus B19 may result in persistent viremia and chronic pure red cell aplasia (PRCA) in immunodeficient patients.
We report a case of parvovirus B19-related PRCA in an AIDS patient. The patient was a 39-year-old male who was confirmed to have HIV infection 4 years earlier. He developed a normocytic anemia 5 months ago (hemoglobin 9.9 g/dL), which worsened slowly. He complained of exertional dyspnea and required a blood transfusion. At admission, his hemoglobin was 4.6 g/dL. The bone marrow examination was consistent with PRCA and positive for parvovirus B19 DNA using the polymerase chain reaction. He was given intravenous immunoglobulin (IVIG) 400 mg/kg for 5 days and his anemia improved. He has been observed without relapse for 3 months. (Korean J Med 75:S913-S916, 2008)
Keywords :HIV, Parvovirus, Red cell aplasia
