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Original Article
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Korean J Med. 2008;75(3):935-941.
- 증례 : 흉선종과 동반된 저감마글로불린혈증(Good 증후군) 1예
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김종연.진재용.이성순.정 훈.이현경.이혁표.최수전 , , , , , ,
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- A case of Good syndrome: Immunodeficiency syndrome associated with a thymoma
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Jong Yeon Kim, Jae-Yong Chin, Sung Soon Lee, Hoon Jung, Hyun-Kung Lee, Hyuk Pyo Lee, Soo Jeon Choi
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- Abstract
- Good syndrome (GS) refers to adult-onset immunodeficiency syndrome (B and T cell immunodeficiency) associated with a thymoma. We present a case of GS involving a 67-year-old female who had oral thrush for 8 years, recurrent sinopulmonary infections for 2 years, and a history of surgery for an anterior mediastinal mass that proved to be a benign thymoma. During the current admission, she suffered from another bout of sinopulmonary infection, and a decreased serum immunoglobulin level was noted on routine chemistry. The IgG, IgA, and IgM immunoglobulin subtypes were decreased markedly. With the diagnosis of GS, she was treated with intravenous immunoglobulin (IVIG), and showed clinical improvement. However, the sinopulmonary infection recurred after 9 months. On re-administering IVIG along with adequate antibiotics, her condition resolved again. (Korean J Med 75:S935-S941, 2008)
Keywords :Good syndrome, Thymoma, Hypogammaglobulinemia, Immunodeficiency
