The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;76(4):506-509.
췌장 선방세포암 1예
김규영, 이화정, 지준호, 이정림, 이원식, 박종훈, 손경락
A case of acinar cell carcinoma of the pancreas
Kyu Young Kim, Hwa Jung Lee, Jun Ho Ji, Jung Lim Lee, Won Sik Lee, Jong Hoon Park, Kyung Rak Shon


Abstract
Acinar cell carcinoma of the pancreas is a rare tumor that constitutes 1~2% of all pancreatic cancers. The clinical and radiologic findings are inconclusive when diagnosing this disease. Acinar cell carcinoma progresses rapidly and metastasizes early, resulting in a poor prognosis. A 41-year-old man was admitted for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography (PET)-CT showed a splenic mass involving the pancreatic tail with increased 18F-fluorodeoxyglucose (18F-FDG) uptake. A primary radical distal pancreatectomy and splenectomy were carried out. The pathology revealed acinar cell carcinoma of the pancreas. Three months later, a gastric recurrence was detected and a total gastrectomy was performed. Four months later, multiple hepatic metastases were found and a left hepatectomy was carried out. During treatment with capecitabine, no evidence of tumor progression was observed for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma that did not progress for 14 months with capecitabine treatment. (Korean J Med 76:506-509, 2009)

Keywords :Pancreas, Carcinoma, Acinar cell, Capecitabine
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