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Original Article
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Korean J Med. 2009;76(1):59-63.
- 전신 경화증에서 관상동맥 혈관연축에 의한 급성 심근경색증 1예
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이창헌, 김나래, 박종선, 김도형, 노동현, 정준훈, 이충원
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- A case of acute myocardial infarction associated with coronary vasospasm in a patient with systemic sclerosis
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Chang Hun Lee, Na Rae Kim, Jong Sun Park, Do Hyung Kim, Dong Hyun No, Joon Hoon Jeong, Choong Won Lee
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- Abstract
- Systemic sclerosis is a chronic, systemic disease that targets the skin, lungs, heart, gastrointestinal tract, kidneys, and musculoskeletal
system. Prominent features are vascular damage, immune activation, and the deposition of extravascular matrix.
Scleroderma heart disease manifests as myocardial fibrosis. Intermittent spasm of the blood vessels in patients with systemic sclerosis
may result in contraction band necrosis, similar to the changes observed in myocardial infarction in patients with atherosclerotic
coronary artery disease. Coronary vasospasm has been demonstrated during attacks of cold-induced Raynaud’s disease.
However, acute myocardial infarction associated with coronary vasospasm in patients with systemic sclerosis has not been
reported.
We describe a rare case of acute myocardial infarction due to coronary vasospasm associated with systemic sclerosis in a
43-year-old woman who presented with severe chest pain. (Korean J Med 76:S59-S63, 2009
Keywords :Myocardial infarction, Coronary vasospasm, Systemic sclerosis
